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Lab Manager, Molecular Operations

Tempus

Tempus

Operations
Posted on May 7, 2025

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

What You’ll Do:

We're on a mission to connect an entire ecosystem to redefine how genomic data is used in clinical settings. We are looking for a Manager to join a laboratory operations team who are passionate and focused on developing state of the art techniques for processing and creating and interpreting vast amounts of genomic and molecular data. You will collaborate with technology, research, and business development teams to develop the most advanced sequencing platform in cancer care.

Shift - Tuesday-Saturday (11:00am-7:30pm)

What you’ll do:

Laboratory Oversight & Performance Metrics

  • Provide high-level oversight of lab operations, ensuring efficient execution of daily workflows while maintaining compliance with CAP, CLIA, and OSHA standards.
  • Deliver regular updates to upper management , summarizing laboratory performance, turnaround times, instrument downtime, productivity, and project progress.
  • Lead initiatives to enhance data tracking and reporting on lab metrics, identifying trends and areas for improvement.

Process Management

  • Oversee and drive multiple continuous improvement initiatives, change orders, and assay implementations from inception to completion.
  • Develop and maintain project timelines, ensuring alignment with laboratory goals, CAP/CLIA regulatory requirements, and resource constraints.
  • Identify bottlenecks in workflow efficiency and implement process optimizations to enhance turnaround time and lab performance.
  • Partner with cross-functional teams, including R&D, quality assurance, and regulatory teams, to ensure seamless project execution and regulatory compliance.
  • Monitor key project milestones, anticipate risks, and proactively address issues to prevent delays or deviations.

Technical Leadership & Team Development

  • Serve as a key liaison between laboratory teams and project stakeholders, translating technical and operational needs into actionable project plans.
  • Mentor and guide laboratory staff, ensuring ongoing professional development and competency in NGS workflows.
  • Collaborate with leadership to develop strategies for resource allocation, process automation, and lab efficiency enhancements.

Regulatory & Quality Compliance

  • Ensure all process improvements, new assay implementations, and workflow modifications meet CAP/CLIA standards.
  • Maintain and update standard operating procedures (SOPs) to align with evolving best practices and regulatory expectations.
  • Oversee QC reviews, ensuring data integrity and validity, and implement corrective actions when test systems deviate from expected performance.

Preferred Qualifications:

  • One of the following educational requirements:
    • M.S. (physical, chemical, or biological science) + at least 4 years pertinent clinical lab experience (at least 2 of which are in a high-complexity molecular laboratory)
    • BS in clinical laboratory science, chemical, physical or biological sciences and at least 7 years of pertinent clinical lab experience in a high-complexity molecular laboratory
  • Demonstrated experience leading assay development and process improvement projects
  • Strong background in Next-Generation Sequencing (NGS) and molecular diagnostics.
  • Proven track record of successfully managing multiple projects, ensuring timely completion and regulatory compliance.
  • Strong organizational skills and project management experience (i.e. familiar with gantt charts and other organizational tools)
  • Strong leadership abilities, with a high degree of personal and professional integrity.
  • Excellent communication and collaboration skills, with experience working cross-functionally across departments.
  • Ability to adapt to a fast-paced, evolving environment and drive strategic improvements.
  • Experience with Lean Six Sigma methodologies, process optimization, and/or laboratory automation is a plus.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.