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Research Scientist II



Chicago, IL, USA
Posted on Tuesday, November 28, 2023

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are looking for a highly skilled Research Scientist to join our Biological Modeling team to support Organoid Based Screening. Our CAP accredited facility develops complex, microenvironment-rich human tumor models for use in a range of studies with our academic and commercial partners to discover next generation cancer therapies. The ideal candidate will have a strong understanding of immuno-oncological cell therapies, systems biology, molecular gene editing, FACS/FLOW, protein detection and scSeq techniques. Post-doctoral and/or industry experience employing human organoid tissue models in high-throughput formats is preferred.

The successful candidate must be able to work in a fast-paced multidisciplinary environment and will be expected to communicate results both internally and to commercial partners.

What You’ll Do:

  • Work in a collaborative, interdisciplinary team of scientists employing gene-editing approaches to perturb cellular pathways with the aim of identifying therapeutic targets
  • Design and execute high-throughput gene-editing, imaging and protein detection workflows
  • Work with automated liquid and plate platforms at all stages of development
  • Execute bulk and scSequencing studies end-to-end
  • Develop analysis pipelines to process and visualize large high-throughput data sets
  • Generate summary reports of screening results and molecular data for customer deliverables


  • Ph.D. in oncology, molecular systems biology, or a related field
  • 2+ years of industry or post-doctoral experience
  • Experience with 3D human tissue models
  • Experience working with next-generation sequencing data
  • Experience coordinating complex experimental workflows across multidisciplinary teams


  • Competitive salary and benefits package
  • Collaborative and supportive work environment
  • Chance to make a real impact on the healthcare industry


We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.